nmr bruker ascend 700 spectrometer (Bruker Corporation)
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Nmr Bruker Ascend 700 Spectrometer, supplied by Bruker Corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Nuclear Magnetic Resonance:Article Title: Antimicrobial Polyketides from the Marine-Derived Fungus Spiromastix sp. SCSIO F190. Article Snippet: Three diphenyl ethers (1−3) and a cyclopentenone (4), together with seven known compounds (5−11), were isolated from the fermentation broth of the marine sediment-derived fungus Spiromastix sp. SCSIO F190.. Compounds 3 and 4 were found to exist as a pair of atropisomers (3a, 3b) and racemates (4a, 4b), respectively.. The planar structures of compounds 1−4 were elucidated on the basis of NMR and HRESIMS data sets. Article Title: OSMAC-Based Discovery and Biosynthetic Gene Clusters Analysis of Secondary Metabolites from Marine-Derived Streptomyces globisporus SCSIO LCY30. Article Snippet: All 1D and Article Title: Synthesis of analogs of dicadalenol, an anti-inflammatory cadinanoid disesquiterpene Article Snippet: Article Title: Hydroanthraquinones from Nigrospora sphaerica and Their Anti-inflammatory Activity Uncovered by Transcriptome Analysis. Article Snippet: Transcriptome analysis is shown to be an effective strategy to understand the potential function of natural products.. Here, it is reported that 11 previously undescribed hydroanthraquinones [nigroquinones A−K (1−11)], along with eight known congeners, were isolated from Nigrospora sphaerica.. Their structures were elucidated by interpreting spectroscopic and spectrometric data including high-resolution mass spectra and nuclear magnetic resonance. Article Title: SAR study of N'-(Salicylidene)heteroarenecarbohydrazides as promising antifungal agents. Article Snippet: Clinically available antifungal drugs have therapeutic limitations due to toxicity, narrow spectrum of activity, and intrinsic or acquired drug resistance.. Thus, there is an urgent need for new broad-spectrum antifungal agents with low toxicity and a novel mechanism of action.. In this context, we have successfully identified several highly promising lead compounds, i.e., aromatic N′-(salicylidene)carbohydrazides, exhibiting excellent antifungal activities against Cryptococcus neoformans, Candida albicans, Aspergillus fumigatus and several other fungi both in vitro and in vivo. Article Title: Ligand-Enabled, Cysteine-Directed β-C(sp<sup>3</sup>)–H Arylation of Alanine in Linear and Cyclic Peptides: Overcoming the Inhibitory Effect of Peptide Bonds Article Snippet: Article Title: Bioactive Piperazic Acid-Bearing Cyclodepsipeptides, Lydiamycins E-H, from an Endophytic Streptomyces sp. Associated with Cinnamomum cassia . Article Snippet: A chemical investigation of the endophytic Streptomyces sp. HBQ95, associated with the medicinal plant Cinnamomum cassia Presl, enabled the discovery of four new piperazic acid-bearing cyclodepsipeptides, lydiamycins E−H (1− 4), and one known compound (lydiamycin A).. Their chemical structures, including absolute configurations, were defined by a combination of spectroscopic analyses and multiple chemical manipulations.. Lydiamycins F−H (2−4) and A (5) exhibited antimetastatic activity against PANC-1 human pancreatic cancer cells without significant cytotoxicity. Article Title: Discovery and optimized extraction of the anti-osteoclastic agent epicatechin-7-O-β-D-apiofuranoside from Ulmus macrocarpa Hance bark. Article Snippet: All NMR spectra were obtained with a Solvent:Article Title: Antimicrobial Polyketides from the Marine-Derived Fungus Spiromastix sp. SCSIO F190. Article Snippet: Three diphenyl ethers (1−3) and a cyclopentenone (4), together with seven known compounds (5−11), were isolated from the fermentation broth of the marine sediment-derived fungus Spiromastix sp. SCSIO F190.. Compounds 3 and 4 were found to exist as a pair of atropisomers (3a, 3b) and racemates (4a, 4b), respectively.. The planar structures of compounds 1−4 were elucidated on the basis of NMR and HRESIMS data sets. Article Title: OSMAC-Based Discovery and Biosynthetic Gene Clusters Analysis of Secondary Metabolites from Marine-Derived Streptomyces globisporus SCSIO LCY30. Article Snippet: All 1D and Article Title: Synthesis of analogs of dicadalenol, an anti-inflammatory cadinanoid disesquiterpene Article Snippet: Article Title: Hydroanthraquinones from Nigrospora sphaerica and Their Anti-inflammatory Activity Uncovered by Transcriptome Analysis. Article Snippet: Transcriptome analysis is shown to be an effective strategy to understand the potential function of natural products.. Here, it is reported that 11 previously undescribed hydroanthraquinones [nigroquinones A−K (1−11)], along with eight known congeners, were isolated from Nigrospora sphaerica.. Their structures were elucidated by interpreting spectroscopic and spectrometric data including high-resolution mass spectra and nuclear magnetic resonance. Article Title: SAR study of N'-(Salicylidene)heteroarenecarbohydrazides as promising antifungal agents. Article Snippet: Clinically available antifungal drugs have therapeutic limitations due to toxicity, narrow spectrum of activity, and intrinsic or acquired drug resistance.. Thus, there is an urgent need for new broad-spectrum antifungal agents with low toxicity and a novel mechanism of action.. In this context, we have successfully identified several highly promising lead compounds, i.e., aromatic N′-(salicylidene)carbohydrazides, exhibiting excellent antifungal activities against Cryptococcus neoformans, Candida albicans, Aspergillus fumigatus and several other fungi both in vitro and in vivo. Article Title: Ligand-Enabled, Cysteine-Directed β-C(sp<sup>3</sup>)–H Arylation of Alanine in Linear and Cyclic Peptides: Overcoming the Inhibitory Effect of Peptide Bonds Article Snippet: Article Title: Bioactive Piperazic Acid-Bearing Cyclodepsipeptides, Lydiamycins E-H, from an Endophytic Streptomyces sp. Associated with Cinnamomum cassia . Article Snippet: A chemical investigation of the endophytic Streptomyces sp. HBQ95, associated with the medicinal plant Cinnamomum cassia Presl, enabled the discovery of four new piperazic acid-bearing cyclodepsipeptides, lydiamycins E−H (1− 4), and one known compound (lydiamycin A).. Their chemical structures, including absolute configurations, were defined by a combination of spectroscopic analyses and multiple chemical manipulations.. Lydiamycins F−H (2−4) and A (5) exhibited antimetastatic activity against PANC-1 human pancreatic cancer cells without significant cytotoxicity. Article Title: Discovery and optimized extraction of the anti-osteoclastic agent epicatechin-7-O-β-D-apiofuranoside from Ulmus macrocarpa Hance bark. Article Snippet: All NMR spectra were obtained with a Column Chromatography:Article Title: Antimicrobial Polyketides from the Marine-Derived Fungus Spiromastix sp. SCSIO F190. Article Snippet: Three diphenyl ethers (1−3) and a cyclopentenone (4), together with seven known compounds (5−11), were isolated from the fermentation broth of the marine sediment-derived fungus Spiromastix sp. SCSIO F190.. Compounds 3 and 4 were found to exist as a pair of atropisomers (3a, 3b) and racemates (4a, 4b), respectively.. The planar structures of compounds 1−4 were elucidated on the basis of NMR and HRESIMS data sets. Article Title: OSMAC-Based Discovery and Biosynthetic Gene Clusters Analysis of Secondary Metabolites from Marine-Derived Streptomyces globisporus SCSIO LCY30. Article Snippet: All 1D and Article Title: Synthesis of analogs of dicadalenol, an anti-inflammatory cadinanoid disesquiterpene Article Snippet: Article Title: Hydroanthraquinones from Nigrospora sphaerica and Their Anti-inflammatory Activity Uncovered by Transcriptome Analysis. Article Snippet: Transcriptome analysis is shown to be an effective strategy to understand the potential function of natural products.. Here, it is reported that 11 previously undescribed hydroanthraquinones [nigroquinones A−K (1−11)], along with eight known congeners, were isolated from Nigrospora sphaerica.. Their structures were elucidated by interpreting spectroscopic and spectrometric data including high-resolution mass spectra and nuclear magnetic resonance. Article Title: SAR study of N'-(Salicylidene)heteroarenecarbohydrazides as promising antifungal agents. Article Snippet: Clinically available antifungal drugs have therapeutic limitations due to toxicity, narrow spectrum of activity, and intrinsic or acquired drug resistance.. Thus, there is an urgent need for new broad-spectrum antifungal agents with low toxicity and a novel mechanism of action.. In this context, we have successfully identified several highly promising lead compounds, i.e., aromatic N′-(salicylidene)carbohydrazides, exhibiting excellent antifungal activities against Cryptococcus neoformans, Candida albicans, Aspergillus fumigatus and several other fungi both in vitro and in vivo. Article Title: Ligand-Enabled, Cysteine-Directed β-C(sp<sup>3</sup>)–H Arylation of Alanine in Linear and Cyclic Peptides: Overcoming the Inhibitory Effect of Peptide Bonds Article Snippet: Article Title: Bioactive Piperazic Acid-Bearing Cyclodepsipeptides, Lydiamycins E-H, from an Endophytic Streptomyces sp. Associated with Cinnamomum cassia . Article Snippet: A chemical investigation of the endophytic Streptomyces sp. HBQ95, associated with the medicinal plant Cinnamomum cassia Presl, enabled the discovery of four new piperazic acid-bearing cyclodepsipeptides, lydiamycins E−H (1− 4), and one known compound (lydiamycin A).. Their chemical structures, including absolute configurations, were defined by a combination of spectroscopic analyses and multiple chemical manipulations.. Lydiamycins F−H (2−4) and A (5) exhibited antimetastatic activity against PANC-1 human pancreatic cancer cells without significant cytotoxicity. Article Title: Discovery and optimized extraction of the anti-osteoclastic agent epicatechin-7-O-β-D-apiofuranoside from Ulmus macrocarpa Hance bark. Article Snippet: All NMR spectra were obtained with a |
